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The production and removal of urea is essential for the elimination of ammonia and toxic nitrogen metabolites

Cardiovascular (Heart and Blood Vessel) Complications In rare but serious cases, B12 replacement can lead to heart and blood vessel problems: Shortness of breath Peripheral edema (swelling in legs and arms) Rapid weight gain Pulmonary edema (fluid in lungs) Congestive heart failure (heart cannot pump effectively) Blood clots in vessels These complications arise from increased blood volume, thicker blood, and sudden changes in how hard the heart needs to work

Regarding the commenter's statement that the HEBA, as proposed, would not benefit the majority of ACOs serving dually eligible and LIS-enrolled beneficiaries, we reaffirm that the HEBA as finalized with modifications will benefit ACOs serving an above-average proportion of LIS enrolled or dually eligible beneficiaries

Serious reactions are extremely uncommon