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Under reaction conditions of pH 5, 1 h and 80 C, RCYs were determined to be 100 0.0%, 91.6 0.4%, 72.2 6.3%, 43.3 10.1% and 3.9 2.7% ( n = 3) for ligand concentrations of 10 4 , 10 5 , 10 6 , 10 7 , and 10 8 M, respectively

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Other promising bioactive agents, including salviolone and vestitol, have been shown to influence calcium signaling and neuroactive ligandreceptor interactions, contributing to cognitive improvement and reduced A deposition in experimental models (Liang et al., 2025)