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High-dose oral cyanocobalamin (1,000 mcg daily) is effective for many patients after sleeve gastrectomy, as a small proportion is absorbed passively without intrinsic factor

It is offered in 30 mL and 10 mL multidose vials, providing clinicians and patients with flexible inventory for individualized treatment programs that aim to potentially support hepatic fat mobilization, potentially enhance mitochondrial fatty-acid oxidation, and potentially improve overall energy metabolism in adults pursuing physician-supervised weight-management or wellness regimens

143 In a randomized placebo-controlled crossover trial in 36 patients with antiphospholipid syndrome, an immune disorder associated with an increased risk of thrombosis, 200 mg CoQ10 daily for one month improved vascular function

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There is no known toxicity level for methylcobalamin supplementation