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The lipid peroxidation process mainly involves the oxidation of fatty acid double bonds, resulting in the formation of hydrogen peroxide, lipid peroxides, and their derivatives (e.g., ,-unsaturated aldehydes)

Dupont, J., Pierre, A., Froment, P

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In contrast, the transcytosis model posits that the transferrin-iron complex undergoes vesicular trafficking across the endothelial cytoplasm without cytosolic release through DMT1 (174)

High-salt diet is an important factor for hypertension, which can deplete Lactobacillus in mice (108), while candesartan can counteract the decrease of Lactobacillus caused by hypertension, and candesartan treatment also increases the intestinal expression of genes encoding tight junction proteins (such as zonula occludens, occludin, and claudin-1), improving increased intestinal permeability caused by hypertension and preventing gut microbiota translocation (105)