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A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression

A study by J.F.S

[DOI] [PubMed] [Google Scholar] 38.Ponsero A.J., Igbaria A., Darch M.A., Miled S., Outten C.E., Winther J.R., Palais G., DAutreaux B., Delaunay-Moisan A., Toledano M.B

Neuropsychiatric Ketamine-induced emergence phenomena are among the more common side effects of ketamine, reported to occur in 10% to 20% of people treated with ketamine

In particular, transforming growth factor-1 (TGF-1) produced by macrophages is an inflammatory growth factor 1 with a strong chemotactic effect on inflammatory cells, and promotes inflammation to damage the lungs 6,32