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In both trials, weight reduction was assessed after 72 weeks of treatment (at least 52 weeks at maintenance dose)

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Typical weight gains did not result in significantly different release profiles of GLP-1 agonists but a weight gain of 46% calculated on the empty capsule which relates to 32.2 mg coating weight gain per size 1 capsule resulted in a dissolution lag time of at least 40 minutes at pH 6