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Methods Search databases We conducted a literature search using electronic databases (PubMed, Web of Science and Google Scholar) on the 8th November 2023 using search terms that include concepts related to ivermectin, resistance, and any of the organisms mentioned in the inclusion criteria (Table 1)

Types of Mutations in the ATP7B gene Gene A category of nucleic acid sequences that function as units of heredity and which code for the basic instructions for the development, reproduction, and maintenance of organisms

Frequency varies based on individual needs, from weekly to monthly

Reinforces extracellular matrix architecture

Most research studies ran for 812 weeks