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Description

Journal of Lipid Research

Administration of CB-1158 (a small molecule inhibitor of arginase) can slow tumor growth rates, block myeloid cell-mediated suppression of T-cell proliferation, and increase the number of tumor-infiltrating CD8 + T cells and NK cells in mouse models of multiple tumors

Tryptophan-rich peptides such as indolicidin and tritrpticin, belong to a newer class of antimicrobial peptides (Chan et al., 2006), wherein this AAA has a binding preference for the interfacial regions of lipid bilayers