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Afroj, S

Consequently, UPR is activated to resolve this protein-folding defect and thus to restore ER homeostasis

10.1126/science.1260144 Science 11 BelloneM.BreviA.HuberS

10.1186/s40360-022-00622-1 241 YangR.ChangQ.MengX.GaoN.WangW

A number of plausible anti-cancer mechanisms have been proposed, such as indirect generation of hydrogen peroxide, enzyme cofactor activities (e.g., collagen synthesis, HIF hypoxic response regulation, TET and JHDM epigenetic regulation), as well as antioxidant and anti-inflammatory functions