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Intertumoral Heterogeneity One of the biggest challenges in treating GBM is intertumoral heterogeneity, which refers to the fact that different regions within a single GBM tumor can have different molecular and genetic profiles

87 Aspartate in cancer TP53 is a gene with the highest mutation frequency in human cancer

Collectively, those findings suggest that the interaction between NRF2 and physiological levels of ANG II in the blood play an important role in maintaining microvessel density, although the mechanisms of this interaction remain unclear