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Tian, Zlateva and Anderson (2013) analyzed data from the eClinicalWorks EHR system showed that patients' demographics, clinic utilization, patient-reported pain scores, opioid prescription records, diagnostic codes, laboratory results, and referrals played an important role in determining an accurate and reliable method for identifying patients with chronic pain

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Overall, a meta-analysis of the immediate effects of e-cigarettes found that acute use of nicotine e-cigarettes was associated with increased heart rate, systolic blood pressure, diastolic blood pressure (172)

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