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Particular attention is given to interventions that enhance synaptic plasticity, activate intrinsic neuroprotective pathways, and promote functional network regeneration (Figure 2)

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Calcitriol intervention significantly restores vitamin D receptor expression, enhances autophagy flux, stimulates mucin/antimicrobial peptide production, and inhibits NF-B-mediated inflammatory responses

USA 96 : 41314136 Hoshino T, Nakamura H, Okamoto M, Kato S, Araya S, Nomiyama K, Oizumi K, Young HA, Aizawa H and Yodoi J (2003) Redox-active protein thioredoxin prevents proinflammatory cytokine- or bleomycin-induced lung injury

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