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Potential side effects observed during clinical research include mild nausea, vomiting, diarrhea, and constipation

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Unlike steroid injections, which primarily reduce inflammation temporarily, these treatments work to restore damaged tissue

Pathohistological examinations of both acute and chronic toxicity revealed that L-NAME caused severe tissue damage (myocardial and hepatic cell necrosis, and necrosis of the lymphoid cells in the spleen) while L-arginine provoked predominantly congestion, edema and hemorrhages in all organs

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