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Radiotherapy is one of the most important modalities for cancer treatment (3-5), particularly for elderly patients, because they generally have multiple co-morbidities and/or poor performance status (6,7), thus excluding surgery and/or chemo-radiation therapy as treatment options

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This is particularly important for expensive peptides, discontinued products, or compounds with long lead times for replacement

One-way ANOVA (with Tukey post hoc test for comparison of multiple means) or, where appropriate, equivalent non-parametric KruskalWallis test (Dunn multiple comparisons) was used as specified in the figure legends

It is also very stable when exposed to heat or acid and is highly safe. Discovery of the Ergothioneine Transporter The primary reason that EGT has received attention in recent years is due to the discovery in 2005 of the ergothioneine transporter (ETT) for the uptake of EGT into cells in humans. As mentioned above, only some microorganisms can produce EGT, but it is now known that EGT is used via ETT in various lifeforms including plants, fish, and mammals