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They propose that under the stimulation of the pro-inflammatory cytokine TNF- , IRF1 can directly bind to the GPX4 promoter region (1,498 to 1,239), affecting GPX4 transcription

FIGURE 3 3.4 Luteolin inhibits integrin IIb3-mediated platelet activation Integrin IIb3-mediated platelet activation is the final common pathway for platelet activation induced by multiple activators (Figures 4A, B)

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