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doi: 10.3389/fnut.2023.1221438 Received 12 May 2023 Accepted 25 July 2023 Published 08 August 2023 Volume 10 - 2023 Edited by Rahele Ziaei, Isfahan University of Medical Sciences, Iran Reviewed by Prabu Paramasivam, University of New Mexico, United States

Finally, degeneration of astrocytes leads to profound morphological changes, including process fragmentation or clasmatodendrosis, signaling irreparable damage and cell death

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Nunes MJ, Carvalho AN, S-Lemos C, Colao M, Cervenka I, Ciraci V et al (2024) Sustained PGC-12 or PGC-13 expression induces astrocyte dysfunction and degeneration

Metabolic water production is therefore proportional to the energy intake