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Indeed, recent studies showed that, in addition to mediating ADCC in in vitro and ex vivo models, isatuximab and daratumumab directly activated NK cells and increased their lytic activity against tumor cells through CD16 and CD38 crosslinking [32, 33]

Other Studies Joint repair effect: In the rabbit collagenase-induced knee osteoarthritis model, AOD 9604 can promote cartilage regeneration, and the effect is better when combined with hyaluronic acid injection

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SC, IM, IP, and oral routes are all used in the published literature, with SC and IM most common

Available online: 47.Gotfredsen C.F., Mlck A.M., Thorup I., Nyborg N.C., Salanti Z., Knudsen L.B., Larsen M.O