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nausea decreases with ongoing usage a steady weight loss occurs in some patients over 2 years (may be related to nausea & CNS-mediated loss of appetite) there is an increased risk of hypoglycemia when exenatide is used with a sulfonylurea The dose of the sulfonylurea may need to be reduced if hypoglycemia occurs when combined with exenatide Most serious : rare & sometimes fatal necrotizing or hemorrhagic pancreatitis When initiating patients on Byetta, watch for signs and symptoms of pancreatitis (including persistent severe abdominal pain, sometimes radiating to the back, which may or may not be accompanied by vomiting)

Egg quality refers to the health and viability of a womans eggs, mainly focusing on the eggs chromosomal integrity

forced-swim and tail-suspension paradigms)

A forest plot showing all areas combined is available in Supplemental Fig

Mice were placed in standard housing, and all animals had access to food, water, and ad libitum throughout the study duration