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Description

(2024) and Kee et al

C.AmorimF

Ramadan et al

(Philos.) 57 , 686691 (2019)

This activation converts pro-interleukin-1 (pro-IL-1) and pro-interleukin-18 (pro-IL-18) into their active forms, which are subsequently released extracellularly, initiating sustained inflammation that disrupts neural circuits and promotes both seizures and depressive behaviors