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However, further in vitro assays and preclinical studies with this NP-delivered metal chelator approach are warranted to improve their targeting capacity to the brain as well as to estimate the level of BBB crossing, chelation efficiency and the related toxicity before clinical applications

Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease

With respect to OM, curcumin applied systemically as capsules significantly improved the mucositis in 4 studies [2, 16,17,18] ( n = 200)

Water is fundamental to cellular function

Uversky VN, Oldfield CJ, Dunker AK (2008) Intrinsically disordered proteins in human diseases: introducing the D 2 concept