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Age-related changes in expression of tissue inhibitor of metalloproteinases-3 associated with transition from the notochordal nucleus pulposus to the fibrocartilaginous nucleus pulposus in rabbit intervertebral disc

While MiR-122 is associated with reduced ALP activity

Zone 1 markers: ARG1, SLBP, and GLS2

1 H, 15 N HSQC spectra of 100 M 15 N-labeled BRD4 ET in 25 mM Tris pH 7.0, 150 mM NaCl, 1 mM TCEP, 10% D 2 O were recorded in the presence of increasing concentrations of ASXLs peptides

Since the discovery of FSP1, more and more GPX4-independent ferroptosis pathways have been discovered in various physiological and pathological processes Drugs targeting GPX4-independent ferroptosis pathway may become a new direction for the treatment of diseases