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Research published in the Journal of Investigative Dermatology has established that IL-1 and TNF-alpha are key drivers of the inflammatory process in acne lesions

Mol Biol Rep 2013;40(1):687-695

Drugs 37 (02), 1318

Indeed, gene ontology analysis for downregulated proteins in SLC25A39/40 double knockout cells revealed a strong enrichment for mitochondrial translation and iron-sulfur cluster containing proteins (Fig