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G4 is a non-canonical DNA structure formed by guanine-rich sequences, consisting of two or more stacked G-quadruplexes (Davis, 2004)

Common applications include: Research on antioxidant defense and oxidative stress Glutathione S-transferase and Phase II detoxification studies Apoptosis pathways and mitochondrial redox balance Models of liver injury, aging, and neurodegeneration Immune response and inflammation experiments Cellular response to toxins and radiation The 500 mg format allows multiple experiments with minimal material waste

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To make matters worse, for alcoholics suffering from depression, it also leads to poor response to antidepressant medication

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