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This process reduces the level of ROS, maintains the cellular redox balance, and protects the tumor cells from oxidative damage [219]

Combined use of amlodipine and folic acid are significantly more efficacious than amlodipine alone in lowering plasma homocysteine and blood pressure among hypertensive patients with hyperhomocysteinemia and intolerance to ACEI: A multicenter, randomized, doubleblind, parallelcontrolled clinical trial