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Rats receiving BPC-157 at doses of 10 micrograms or 10 nanograms per kilogram showed improvement across every measured outcome: clinical recovery, microscopic nerve architecture, morphometric analysis, electromyography (EMG), and functional walking recovery measured by the sciatic functional index

Similar results were found at mRNA expression level with downregulation of ZO-1 and occludin before the onset of arthritis (Supplementary Fig

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