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Integration of peripheral transcriptomics, genomics, and interactomics following trauma identifies causal genes for symptoms of post-traumatic stress and major depression

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Kang J, Chun J, Hwang JS, Pan C, Li J, Boese AC, et al

In our opinion, the increase in hydrogen sulfide production in glutathione-treated old animals was due to an increase in the expression of 3-MST (by 25%), or probably the activity of this mitochondrial enzyme due to an excess of the substrate L-cysteine, which is common for the synthesis of this gaseous mediator and glutathione