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To solve the paradox that pre-existing high concentrations of ROS in the TME can conversely inhibit immunity, the most advanced strategy is to develop multifunctional nanovaccines that first clear, then activate. Such vaccines can first use their material properties to scavenge the inhibitory ROS in the TME, creating a favorable environment for immune cells, and then strongly activate DCs by releasing immune agonists, ultimately triggering a systemic anti-tumor immunity [265]

Semaglutide is prescribed as a weekly subcutaneous injection administered in the abdomen, with injections alternating locations

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The main phenolic compound in spearmint extract responsible for its ACEI effects has been identified as rosmarinic acid (373)

[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Innes H., Buch S., Hutchinson S., Guha I.N., Morling J.R., Barnes E., Irving W., Forrest E., Pedergnana V., Goldberg D., et al