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[PubMed] Karlstetter, M., R

doi: 10.1016/s0195-6701(05)80007-6 139 WangTZhangJWangYLiYWangLYuYet al

Somashekar et al., 2012

Plast reconstructive Surg (2018) 142(1):23e33e

Over years or decades, chronic exposure to a particular suite of environmental and genetic factors at the base elicits a trajectory of impaired mitochondrial biology that maximally impacts particular subsets of mitotypes in the bulk, which eventually surfaces as the hallmark features of a particular neurodegenerative disorder at the tip