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10.1038/3311 Nat

[1] [2] Other less common side effects that may not necessarily need medical attention include dizziness, flushing, headache, sleepiness, and trouble sitting still

As observed in disease models of gastroparesis (Tseng et al., 2022), chronic constipation (Wang et al., 2023), functional dyspepsia (Tait and Sayuk, 2021), and irritable bowel syndrome (IBS) (Mayer et al., 2023), there is a notable loss of enteric neurons and ICCs, along with a reduction in the size and quantity of ganglia, underscoring the critical role of the ENS in maintaining GI function and motility

In cases where surgery is not feasible or preferred by the owner due to factors like advanced age anesthesia risks cost prolonged post-op confinement extended recovery time Additionally, for dogs with multiple orthopedic issues alongside the ACL tear, such as elbow dyspepsia hip problems arthritic hocks In cases where surgical repair of only one problem may not be the most effective approach, stem cell therapy can offer pain relief for multiple injuries simultaneously