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CRISPR-Cas9 deletion of -cell 2A -adrenergic receptor in INS-1E cells reduces DAs ability to inhibit GSIS in the KO cells

Similarly, nutrient supplementation elevated both ATP levels and bioluminescent output without affecting bacterial numbers, supporting the use of lux-based bioluminescence as a readout of metabolic activity (Extended Data Fig

( D - F ) Scatter plots of the log-normalized expression levels of Myh1 and Myh4 in the myonuclei clusters Type IIx ( D ), Type IIb ( E ), and Type IIx/IIb ( F )