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Spinal surgery to remove the degenerated disc and fuse the adjacent spinal segments may cause degeneration and instability of the neighboring discs (Karppinen et al., 2011)

The mechanism by which food-derived alkaloid compounds induce ferroptosis to inhibit tumors is detailed in Figure 7B

optionally substituted polyether, aryl having 6 to 10 ring atoms, C3-C8 cycloalkyl, heterocycloalkyl having 3 to 10 ring atoms, heteroaryl having 5 to 10 ring atoms, and any combination thereof,said alkyl and alkenyl being optionally interrupted by one or more heteroatom or chemical groups selected from -O-, -S-, -C(O)-, -NR"-, -C(O)NR"-, -NR"-C(O)-, -NR"-C(O)-NR-, -NR"-C(O)-O-, -O-C(O)NR"- and triazole,R" and R being independently selected from H and C1-C6 alkyl,and pharmaceutically acceptable salts thereof

Acta 1842, 721

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