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Functional improvement (strength, range of motion) within 3-4 weeks

11 September 2023

In the documented protocol, daily during the 4-week activation phase, then 5/week for weeks 58, then 23/week for maintenance

Consistent with the PAMPA measurements, the 1,8-diMQ analogue exhibited very low bi-directional transport in the Caco-2 cell assay (Table 5)

Compared to placebo, B-vitamin supplementation in these older subjects also improved a measure of executive function, a secondary outcome of the trial (93)