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However, in GCLM KO mice, genes encoding lipid synthesis enzymes, Fasn and Scd , were further down-regulated, whereas Fads1 was up-regulated by ethanol, the net effect of which would be expected to result in lower levels of total TG and increases in the relative abundance of certain lipid species

HeLa cells were treated with a series of concentrations of buthionine sulfoximine (BSO) for 72 h, a specific inhibitor for the enzyme required in the first step of GSH synthesis (Fig

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A previous study showed that the transcription of SQSTM1 was increased in the case of ER stress 51