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Decreased autophagosomes were also observed by fluorescence and TEM following the BX795 treatment (Fig

Previous studies have demonstrated that nanostructured systems offer significant advantages in enhancing targeted delivery efficiency, reducing off-target toxicity, and promoting cooperative proteinprotein interactions

Results Plumbagin showed higher bloodbrain barrier penetration ability than that of lapachol and shikonin and elicited significant growth inhibitory effects in vitro and in vivo