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Specifically, O 2 is produced by NOS, uncoupled eNOS, xanthine oxidase, cyclo-oxygenase (COX), and the enzyme of the mitochondrial respiratory chain (79)

Erastin induces apoptotic and ferroptotic cell death by inducing ROS accumulation by causing mitochondrial dysfunction in gastric cancer cell HGC27

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Hydration is key, both internally by drinking enough water and externally with hydrating skincare

We can also ask which specific types of Fe cofactor are essential