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Subsequent intravenous (IV) administration to both mammalian liver cell-lines (HepG2) in vitro and CTLN2 mouse model in vivo corrected the subcellular localisation and expression of a fully functional citrin protein in liver mitochondria, i.e., almost equivalent to 25% of wild-type expression levels [134]

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Ezpeleta, M

Chemico-biological aspects of (-)-epigallocatechin-3-gallate (EGCG) to improve its stability, bioavailability and membrane permeability: current status and future prospects