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Hypoxia-inducible factors: master regulators of hypoxic tumor immune escape

The oldest patient developed intractable seizures at the age of 3 and continues to be treated with anticonvulsants to reduce the occurrence of breakthrough seizures

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Yet, the precise spatiotemporal causal sequence among these three elements remains unconfirmed by longitudinal human studies

Such diseases often arise from impaired vascular function, leading to severe complications such as myocardial infarction and cerebrovascular accidents (Prakash Babu et al., 2019