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This synergistic effect is likely attributable to LDRT-induced intracellular generation of HO through water radiolysis, with the elevated HO serving as a key substrate for Cu-mediated Fenton-like reactions

Managing uremic toxins with diet and use of absorbents and phosphate binders In patients with CKD, uremic toxins IS and pCS accumulate in the blood because of decreased excretion in the kidneys and play a key role in the progression of CKD

Chin Med 21 , 117 (2026)

For example, antigen presenting cells may be targeted through the injection of nanoparticle-bound antigens into the dermal or subcutaneous tissue near the lymph node of interest

Studies utilizing mice lacking GPX in PAECs have demonstrated that the absence of GPX leads to reduced phosphorylation of protein kinase B (Akt), heightened activity of NF-B, and significantly increased expression of vascular cell adhesion molecules