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Symptoms of iron deficiency anemia include fatigue, pale skin, weakness, shortness of breath, headache, dizziness or lightheadedness, cold hands and feet, irritability, tongue inflammation or soreness, brittle nails, fast heartbeat, and poor appetite (Mayo Clinic 2011c)

Imagine an apple that turns brown when left in the open air

Porcine ear skin was used due to its close structural resemblance to human skin, including comparable hair follicle density, stratum corneum (SC) thickness, stratified multilayered, keratinising epithelium and viable epidermis thickness [25, 26]

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Ascorbate in the apoplast generates ROS which promote fruit ripening (Green and Fry, 2005