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Notable upregulated genes in melatonin-treated ILC2s were components of the molecular circadian clock such as Arntl , along with genes involved in glutathione synthesis such as Gclc ( Figure 5C )

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Considering how the implementation of high-dose VitC may be a breakthrough in the treatment of cancer patients with poor prognosis and few available treatment options, it is fair to conclude that further clinical examination of this promising and non-toxic cancer treatment modality is not only warranted, but is in fact highly needed