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10.1152/ajpendo.00255.2002 217

TLR pathway activation leads to secretion of pro-inflammatory cytokines, like interleukin (IL)-1, IL-6, and tumor necrosis factor-, as well as type 1 interferon

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All authors contributed to the article and approved the submitted version Acknowledgments The authors thank Servio de Imuno-Hemoterapia from Instituto Portugus de Oncologia de Lisboa Francisco Gentil (IPOLFG EPE) for providing the buffy coats from healthy donors

Likewise, for Sulforaphane (SFN)an isothiocyanate OSC with promising host-directed activitya recent study demonstrated that microencapsulation using whey- or pea-protein matrices significantly enhanced bioaccessibility during simulated gastrointestinal digestion and improved absorption in a Caco-2/HT29 intestinal cell model compared with unprotected SFN or crude broccoli extract