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Notably, high-grade lesions were associated with reduced IL1B and IL18 transcription, suggesting a potential immune evasion mechanism employed by HPV to promote persistence [214]

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Ferroptosis, a new form of cell death, plays an important role in glioma cell and immune cell

In patients with no CMV-specific immune reactivity at baseline (n = 31) expansion of CMV-specific T-cells was demonstrated in 20 (64.5%) within 100 days (145)

This approach categorizes internal tumor cells into distinct subclones, revealing the internal heterogeneity of GBM