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GFR 30-49 ml/min: 250-750 mg q12hr

Early observational data suggests that patients on GLP-1 therapy for weight loss may see B12 levels decline by 10-15% over six to twelve months, depending on baseline status and dietary intake

Storage Requirements Requires Refrigeration NON-RETURNABLE

In the UK, these products are regulated as food supplements under food law, not as licensed medicines, and formulations can vary considerably between brands

Recent experimental studies have suggested that moderately elevated homocysteine levels are a causal risk factor for atherothrombotic disease because they affect both the vascular wall structure and the blood coagulation system