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Sinclair is a superstar among a group of researchers who have harnessed science and technologys latest advances in an effort to parse out, for the very first time, the biological mechanisms of aging in hopes of slowing or even reversing the process

If tremors exist or body movement is greatly affected, a referral may be given to a neurologist to rule out neurodegenerative diseases such as Parkinson's Disease

Unlike fatty acid metabolism, which is primarily controlled by SREBP-1c, cholesterol homeostasis is governed by SREBP2, a transcription factor that senses intracellular cholesterol levels and modulates cholesterol synthesis, uptake, and storage accordingly [50]

(1995) Vaccine 13: 202-208)

ASCT, in combination with high-dose chemotherapy (usually melphalan), is a treatment that, for many eligible myeloma patients, offers a very good chance for a long-lasting response