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Homocysteine metabolism and glutathione (GSH) synthesis. The Download Scientific Diagram Biomolecules: Homocystinuria and its management (practice) Khan Academy Vitamin B12 is the essential cofactor that lets the Folate Cycle hand a methyl group to homocysteine (via methionine synthase), enabling methionine SAMe production; SAMe is the cell's universal methyl donor Homocysteine exchange across skeletal muscle in patients with chronic kidney disease Garibotto 2023 Physiological Reports Wiley Online Library CBS: Your Homocysteine Regulation Powerhouse! CBS directs homocysteine into the transulfuration pathway, fueling glutathione production for detox & antioxidant support. It needs vitamin B6 & selenium Mutations can disrupt

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