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Astaxanthin has been shown to increase BDNF levels studies in rodents and human cells (in vitro) Improvements in memory are observed in some studies but with variability across demographics These neurocognitive benefits may be through reduced lipid peroxidation Longevity pathways: Astaxanthin mechanistically modulates key longevity genes, including FOXO3, Sirt1, Klotho, and Nrf2

Transmembrane and secreted proteins are first synthesized in the endoplasmic reticulum (ER) and are trafficked via transport vesicles to the Golgi

Their spiny or bristly shapes are characteristics of pyramidal neurons of the cerebral cortex, the hippocampus, and the amygdala

Molecular Pharmacology, Volume 106, Issue 4, 164 172 Mimicking exercise: what matters most and where to next