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NAD + deficiency can also be endogenous, a secondary consequence of metabolic disease

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J Neurochem 2014

The authors highlighted that the present GSTM1 and GSTT1 genotypes, as well as the wild-type GSTP1 genotype, are associated with high levels of 8-OHdG and MDA and low levels of antioxidant activity

Two novel monothiol glutaredoxins from Saccharomyces cerevisiae provide further insight into ironsulfur cluster binding, oligomerization, and enzymatic activity of glutaredoxins