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10.1161/JAHA.117.006347 48

While it is not FDA-approved, clinicians and patients alike are watching it closely because it represents a new direction in peptide therapy for weight loss where its triple-agonist mechanism is something that many did not expect

However, clinical evidence remains limited, and future studies are needed to verify whether combined nutritional or pharmacological interventions can provide protective effects during exercise in patients with mitochondrial myopathy

Therefore, the specific physiopathology of the aging heart should be considered before applying NAD+ supplementations