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For example, changes in the composition and function of gut microbiota have been observed in conditions such as Alzheimers disease, Parkinsons disease, and depression (Liu et al., 2023)

This antioxidant effect also enhances the activity of direct-acting antivirals such as telaprevir, especially in telaprevir-resistant replicon cells ( Beyond HCV, PYC also modulates host factors implicated in viral replication and immune regulation, including long non-coding IFN-induced protein-44 (lnc-IFI-44), polycystic kidney disease 1-like 3 (Pkd1l3), and ubiquitin-specific peptidase 31 (Usp31) ( PYC has also been reported to inhibit HIV-1 entry and replication ( Importantly, PYCs antiviral activity extends beyond direct viral inhibition to include complementary host-directed effects

2017 Mar 20;9(3)

doi: 10.1016/j.curtheres.2014.01.001 [17] Jacobson Bensky M, Ayalon-Dangur I, Ayalon-Dangur R et al

Shiina, K