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To try to reconcile these findings, the authors speculated that the differences could be ascribed to the amount of ROS, as cysteines can be susceptible to different post-translation modifications, which can either activate or inhibit protein function

Because conjugation of the electrophilic AFB 1 -8,9-epoxide with GSH is an alternative fate to binding to nucleophilic centers in cellular macromolecules, GSTs play a critical role in the protection of tissues from the deleterious effects of bioactivated AFB 1 , and tissues vary considerably in both GST concentration and distribution of specific GST isoforms

Free Radic Res 24, 123134 (1996) 32

Tan explained that melanotan is a synthetic peptide which is made in a lab

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